On August 24, 1979 he united in marriage with his wife of 35 years, Brenda Sue Lawton Powell. To this union six sons also survive: Thomas Isaac Powell II, George Monroe (Marissa) Powell II, James Harrison (Samantha) Powell, Daniel Benjamin Powell, Hobert Jefferson (Christy) Powell and Timothy Doyle (Brittany) Powell.
Also surviving are his seven grandchildren: Tabitha, Kevin, Trey, Lexie, Ava, Sierra and Korbyn; surviving is his sister: Cathy Huff and brothers: Dale (Mary) Powell and Bro. Tommy (Michelle) Powell. His brother Ronnie precedes him in death.
George was employed at TP Mechanics in Lexington and was a member of the Big Springs Baptist Church. He was greatly loved by his family and friends and will be sadly missed by all.